#ثريد

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Asthma

للمختصين في المجال الصحي

كوب القهوة معاك ☕️ واستمتع ❤️ https://t.co/sX2xFcV1zh

Definition:

chronic inflammatory disease of the respiratory system (narrowing airway passages),characterized by bronchial

hyperresponsiveness, episodic exacerbation(asthma attacks), and reversible airflow obstruction.

Note ? Asthma considered as obstructive and it’s reversible https://t.co/ruRTPAWd7t

Etiology:

The exact etiology of asthma remains unknown.

Asthma triggers:

1-allergic asthma:

• Environmental allergens: pollen (seasonal), dust mites, domestic animals, mold spores.
• Allergic occupational asthma from exposure to allergen in the workplace (e.g., flour dust) https://t.co/69Ud5vRgm0

2-non allergic asthma

• Viral respiratory tract infections
• Cold air
• Physical exertion
• GERD
• Chronic sinusitis or rhinitis
• Medication: like ASA, NSIDS and beta blockers
• Irritant-induced asthma (e.g., from exposure to solvents, ozone, tobacco or wood smoke). https://t.co/138OqFH6WV

Pathophysiology:

Allergen bind to (T-helper ll cells) release:

•interleukin-4

•interleukin-5

•interleukin-4 activate plasma to release more (IgE) it’s bind to mast cells to release histamine and leukotrienes.

•interleukin-5 eosinophils to release leukotrienes and proteases.