موضوعنا اليوم عن #parkinson الشلل الرعاشِ اهم امراض الجهاز العصبي! ? أُصاب فيه اشهر ملاكم في العالم ? يلا نعرف تفاصيل المرض في هذا الثريد??

Parkinson disease الشلل الرعاشِ (PD) ??‍is a chronic, progressive movement disorder resulting from loss of dopamine in the brain, characterized by rigidity,bradykinesia, postural disturbances, and tremor

داء حركي ببسب فقد الدوبامين في الدماغ يظهر في شكل تصلب، بطء حركة وارتعاش https://t.co/lomYobOWH7

غالبا اعمار المصابين فيه من ٥٠ سنة ل٨٠ سنة ??‍??

PD develops insidiously and progresses slowly over many years (2) (symptoms of PD are progressive, within 10 to 20 years, significant immobility results for most pt )

Pathophysiology ?

The loss of dopamine producing neurons result in imbalance ? between dopamine”an inhibitory neurotransmitter” and “excitatory neurotransmitter “ ACh ➡️ leads to an excess of excitatory ACh at the synapse, and consequent rigidity, tremors, and bradykinesia

Risk factors

??‍Age: 60 years of age or older

✅Genetics

Gender: Men more than women

? Exposure to toxins: Ongoing exposure to herbicides and pesticides increases the risk of Parkinson's disease